Anti-SRP Ab

Test Code: 196
CPT Codes: 83516
Methodology: RIPA
Specimen Requirements: 1 mL serum, ambient, refrigerated or frozen, or EDTA (lavender top) plasma can be used
Turn Around Time: 10 – 14 Days
Special Instructions: None
Clinical Utilities: SRP is considered a Myositis-specific antibody.  It is commonly found in Polymyositis, ILD and arthritis, and occasionally in dermatomyositis. Anti-SRP was first described in a polymyositis patient in 1986.  Anti-SRP antibodies are rare, in only about 4% of myositis patients, and are often found in African American females with an acute, severe onset of polymyositis, with poor response to therapy.