Anti-Chromatin Ab, IgG

Test Code: 578
CPT Codes: 86235
Methodology: EIA
Specimen Requirements: 1 mL serum, ambient, refrigerated or frozen
Turn Around Time: 1 – 3 Days
Special Instructions: None
Clinical Utilities: Chromatin is comprised of native DNA wrapped around the (H2A-H2B-H3-H4)2 histone octamer, with histone H1 and some non-histone proteins associated.  The presence of chromatin antibodies can be used in conjunction with clinical findings and other laboratory tests to aid in the diagnosis of drug-induced lupus (DIL) and Systemic Lupus Erythematosus (SLE).