Anti-DNA Ab (Single Stranded)

Test Code: 14
CPT Codes: 86226
Methodology: EIA
Specimen Requirements: 1 mL serum, ambient, refrigerated or frozen
Turn Around Time:  3 – 5 Days
Special Instructions: None
Clinical Utilities: Single-stranded DNA (ssDNA) autoantibodies aid in the diagnosis of Systemic Lupus Erythematosus (SLE) and related connective tissue diseases.  Anti-ssDNA abs are found in 80-90% of SLE patients during the administration of certain drugs (e.g., procainemide or quinidine) and other autoimmune diseases including rheumatoid arthritis, scleroderma, linear localized scleroderma, polymyositis-dermato-myositis, Sjogren’s syndrome, mixed connective tissue disease (MCTD) and overlap syndromes, myasthenia gravis, chronic active hepatitis, infectious mononucleosis, chronic glomerulonephritis, and billiary cirrhosis.