Positive Anti-Sci-70 (Anti-Topoisomerase), Anti-Th/To, Anti-Fibrillarin (U3 RNP) and Anti-RNA Polymerase III denote a poort prognosis.  Positive Anti-Centromere, Anti-U1RNP and Anti-PM/Sci denote a good prognosis.

• Anti-Nuclear Ab by IFA
• Anti-Scl-70 (Anti-Topoisomerase I) by EIA
• Anti-RNA Ploymerase III by EIA
• Anti-Centromere by IFA
• Anti-Th/To by IPP
• Anti-U1 RNP by EIA
• Anti-Fibrillarian (U3 RNP) by IPP
• Anticardiolipin Abs by EIA

3 mL Serum, ambient, refrigerated or frozen